Effect of carboxymethyl chito-oligosaccharide on cysteine absorption in intestinal porcine epithelial cells

Effect of carboxymethyl chito-oligosaccharide on cysteine absorption in intestinal porcine epithelial cells

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Oxidative stress is associated with retarded growth and the initiation and progression of diseases in pigs.The carboxymethylation of chito-oligosaccharide (COS) can improve its antioxidant activity for such issues.Herein, an orthogonal experiment L9 (34) test design was used to optimise the preparation conditions of carboxymethyl (CM)-COS.Fourier-transform infrared analysis evidenced the carboxymethylation of COS, and an in vitro study indicated echofix spring reverb that the hydroxyl radical scavenging ability of CM-COS is superior to that of COS.

CM-COS can also better promote the absorption of cysteine and increase the expression of the amino acid transport system b0,+ in intestinal porcine epithelial cells.The results suggested that CM-COS can effectively resist oxidative damage by promoting cysteine absorption mediated by transport read more system b0,+, which provides important information regarding the antioxidative damage application of COS and CM-COS in the pig farming industry.